Summary
Memorize the mechanism of action of various antimicrobial agents
| Drug (memorize) | Mechanism of action (memorize) |
|---|---|
| penicillin | block cell wall synthesis by inhibition of peptidoglycan cross-linking |
| ampicillin | block cell wall synthesis by inhibition of peptidoglycan cross-linking |
| ticarcillin | block cell wall synthesis by inhibition of peptidoglycan cross-linking |
| piperacillin | block cell wall synthesis by inhibition of peptidoglycan cross-linking |
| imipenem | block cell wall synthesis by inhibition of peptidoglycan cross-linking |
| aztreonam | block cell wall synthesis by inhibition of peptidoglycan cross-linking |
| cephalosporins | block cell wall synthesis by inhibition of peptidoglycan cross-linking |
| bacitracin | block peptidoglycan synthesis |
| vancomycin | block peptidoglycan synthesis |
| cycloserine | block peptidoglycan synthesis |
| polymixins | disrupt bacterial/fungal cell membranes |
| amphotericin B | disrupt fungal cell membranes |
| nystatin | disrupt fungal cell membranes |
| fluconazole/azoles | disrupt fungal cell membranes |
| sulfonamides | block nucleotide synthesis |
| trimethoprim | block nucleotide synthesis |
| quinolones | block DNA topoisomerases |
| rifampin | block mRNA synthesis |
| chloramphenicol | block protein synthesis at 50 S ribosome |
| erythromycin/macrolides | block protein synthesis at 50 S ribosome |
| lincomycin | block protein synthesis at 50 S ribosome |
| clindamycin | block protein synthesis at 50 S ribosome |
| streptogramins | block protein synthesis at 50 S ribosome |
| linezolid | block protein synthesis at 50 S ribosome |
| aminoglycosides | block protein synthesis at 30 S ribosome |
| tetracyclines | block protein synthesis at 30 S ribosome |
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